Test measuring Estradiol level, a female sex hormone produced by the ovaries, adrenal gland and also placenta during pregnancy.
Measuring the circulating levels of estradiol is
important for assessing the ovarian function and monitoring follicular
development for assisted reproduction protocols. Estradiol plays an essential
role throughout the human menstrual cycle. Elevated estradiol levels in females
may also result from primary or secondary ovarian hyperfunction. Very high
estradiol levels are found during the induction of ovulation for assisted
reproduction therapy or in pregnancy. Decreased estradiol levels in females may
result from either lack of ovarian synthesis (primary ovarian hypofunction and
menopause) or a lesion in the hypothalamus-pituitary axis (secondary ovarian
hypofunction). Elevated estradiol levels in males may be due to increased
aromatization of androgens, resulting in gynecomastia.